trachomatis positive specimens from females and males were collected for genotyping. Additionally, we wanted to set up a method for detection of the Swedish nvCT and to study the occurrence of this variant in Finland. trachomatis (types D–K and L1–元) in urogenital samples. The purpose of this work was to set up a real-time PCR-based method for genotyping C.
Jukka Suni, HUSLAB personal communication). At the same time, the proportion of urogenital samples that tested positive by Cobas TaqMan CT Test, old version (Roche), decreased slightly in Southern Finland (Dr. trachomatis (nvCT) with a 377 base pair deletion in the cryptic plasmid. trachomatis cases in Sweden, which was caused by the appearance of a new variant of C. In 2006, there was an unexpected fall in C. trachomatis has also a cryptic plasmid which is commonly used as a target sequence in diagnostic NAATs. trachomatis types A–C cause trachoma, types D–K cause urogenital infections, and types L1–元 cause lymphogranuloma venereum (LGV). trachomatis major outer membrane protein (MOMP) first leads to the identification of ≥15 different serovars, and sequence differences in the ompA gene, especially in the areas coding the variable domains of MOMP, later confirmed this discrimination. trachomatis infections are diagnosed mainly with sensitive and specific nucleic acid amplification tests (NAATs), but these tests do not differentiate between genotypes. Lately, there has been around 14 000 notified cases annually (250 cases/100 000 inhabitants). trachomatis infections has been officially notified in Finland, and the number of notifications has been increasing. trachomatis constitute an important target group for public health interventions. The infections are very prevalent among adolescents, and reinfections are common. Even asymptomatic infections can lead to serious sequelae such as infertility and ectopic pregnancy. Subsequently, they identified 92 more people with this variant from all regions of the Netherlands, bringing the total number of confirmed cases to 109 people.Įxperts say that further studies of this variant may reveal new parts of the virus that can be defeated thanks to drugs.Chlamydia trachomatis, an obligate intracellular bacterium, is worldwide a common cause of sexually transmitted infections. Two cases were in Switzerland and Belgium, while 15 variants of VB samples were taken from individuals in the Netherlands. The analysis showed that VB originated in the 1980s, and its distribution has been decreasing since 2010.Īccording to recent studies, 17 cases of the new strain were detected in HIV samples collected from all over Europe and Uganda. In addition, they report that the rapid deterioration of health after VB infection means that early detection and treatment are “critical”.Īt the same time, independent experts say that the found variant of the HIV strain is not so dangerous. This means, scientists explain, that infected people are more likely to transmit the virus to others. The VB variant also has a viral load from 3.5 to 5.5 times higher than the current strain. Studies have found that the VB strain damages the immune system and weakens a person’s ability to fight everyday infections and diseases faster than previous versions of the virus. This is reported by the Daily Mail with reference to a study by the Institute of Extensive Data at Oxford University and the Dutch HIV Monitoring Foundation.Īccording to a study by Oxford University, at least 109 people have been infected with the new virus.
The strain damages the immune system twice as fast as other variants of the virus.
In the Netherlands, scientists have discovered a new super mutant strain of HIV called VB. The new strain of VB damages the immune system and weakens a person’s ability to fight everyday infections and diseases than previous versions of the virus.
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